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Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that makes them likely to benefit from naltrexone, weighed against about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are still available online ( inside journal Neuropsychopharmacology and you will be published in a upcoming print edition with the journal. Using two separate drugs to shed weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you should err to the side of caution and permit the FDA do its job and demand some study be done so that the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on their own medications. Researchers discovered that participants using this drug for the year, lost weight within one month and have kept the weight off throughout the 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them far better and safer. Combo-pilling could be the newest fad or even better the newest to come under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular will be the fact that as of right now there are no long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug also can raise blood pressure and heart rate, and shouldn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. Most of the combinations which are used to enhance fat loss involve an amphetamine plus an antidepressant. Phentermine and Prozac certainly are a popular combination that have been around for some time, and even though it has been around nobody wants to truly combine both the and try to get FDA approval to promote it as a fat loss pill. Right there should raise some warning flags if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something has to be wrong while using combination. In fairness there is one fat loss combination pill that's in front of the FDA now Contrave?which couples naltrexone, used to treat alcohol and drug addiction, with all the antidepressant bupropion (Wellbutrin, Zyban) it is often given the just do it to move forward by an FDA advisory committee, but at the time of yet hasn't been approved.